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| 05.06.2021 | 16:00 | SSD Tiferno Lerchi | - | Follonica Gavorrano | 1:0 | |
| 06.06.2021 | 16:00 | ACN Siena 1904 | - | Aquila Montevarchi | 1:3 | |
| 16:00 | ASD Cannara | - | Scandicci Calcio | 2:1 | ||
| 16:00 | Calcio Flaminia | - | San Donato Tavarnelle | 2:1 | ||
| 16:00 | Grassina | - | Montespaccato | 3:2 | ||
| 16:00 | Ostia Mare | - | SC Trestina | 1:1 | ||
| 16:00 | US Pianese | - | Foligno Calcio | 1:0 | ||
| 16:00 | AC Sangiovannese | - | Badesse Calcio | 1:1 | ||
| 16:00 | UC Sinalunghese | - | ASD Trastevere | 0:1 |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Aquila Montevarchi | 31 | 18 | 8 | 5 | 59:31 | 28 | 62 |
| 2 |
|
ASD Trastevere | 31 | 17 | 7 | 7 | 52:32 | 20 | 58 |
| 3 |
|
SC Trestina | 31 | 13 | 11 | 7 | 43:30 | 13 | 50 |
| 4 |
|
Follonica Gavorrano | 31 | 13 | 8 | 10 | 42:33 | 9 | 47 |
| 5 |
|
US Pianese | 31 | 12 | 11 | 8 | 38:30 | 8 | 47 |
| 6 |
|
San Donato Tavarnelle | 31 | 12 | 11 | 8 | 40:38 | 2 | 47 |
| 7 |
|
ASD Cannara | 31 | 12 | 10 | 9 | 38:40 | -2 | 46 |
| 8 |
|
SSD Tiferno Lerchi | 31 | 12 | 8 | 11 | 40:40 | 0 | 44 |
| 9 |
|
ACN Siena 1904 | 31 | 12 | 8 | 11 | 39:39 | 0 | 44 |
| 10 |
|
AC Sangiovannese | 31 | 11 | 9 | 11 | 38:37 | 1 | 42 |
| 11 |
|
Montespaccato | 31 | 11 | 7 | 13 | 37:39 | -2 | 40 |
| 12 |
|
Badesse Calcio | 31 | 10 | 9 | 12 | 44:43 | 1 | 39 |
| 13 |
|
Calcio Flaminia | 31 | 9 | 10 | 12 | 40:51 | -11 | 37 |
| 14 |
|
Ostia Mare | 31 | 8 | 12 | 11 | 44:48 | -4 | 36 |
| 15 |
|
Foligno Calcio | 31 | 9 | 7 | 15 | 29:41 | -12 | 34 |
| 16 |
|
Scandicci Calcio | 31 | 8 | 7 | 16 | 34:44 | -10 | 29 |
| 17 |
|
Grassina | 31 | 5 | 12 | 14 | 28:45 | -17 | 27 |
| 18 |
|
UC Sinalunghese | 31 | 4 | 11 | 16 | 24:48 | -24 | 23 |
| Promotion | |
| Play-off | |
| Relégation |
