 |
 |
|
|
| 05.02.2022 | 18:30 | Aris Saloniki | - | Volos NFC | 0:2 (0:0) | |
| 18:30 | Panetolikos | - | PAS Giannina | 0:1 (0:0) | ||
| 06.02.2022 | 14:00 | AEK Athen | - | Apollon Smyrnis | 3:0 (0:0) | |
| 16:15 | Ionikos Nikea | - | Olympiakos Piraeus | 0:3 (0:1) | ||
| 18:30 | PAOK Saloniki | - | Panathinaikos | 2:1 (0:1) | ||
| 16.02.2022 | 17:00 | Atromitos | - | OFI Heraklion | 2:2 (2:0) | |
| 23.02.2022 | 16:30 | Lamia | - | Asteras Tripolis | 0:2 (0:2) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Olympiakos Piraeus | 22 | 17 | 5 | 0 | 42:12 | 30 | 56 |
| 2 |
|
PAOK Saloniki | 22 | 14 | 3 | 5 | 46:23 | 23 | 45 |
| 3 |
|
AEK Athen | 22 | 12 | 4 | 6 | 38:23 | 15 | 40 |
| 4 |
|
Aris Saloniki | 22 | 11 | 5 | 6 | 24:18 | 6 | 38 |
| 5 |
|
Asteras Tripolis | 22 | 10 | 5 | 7 | 24:20 | 4 | 35 |
| 6 |
|
Panathinaikos | 22 | 10 | 3 | 9 | 34:20 | 14 | 33 |
| 7 |
|
PAS Giannina | 22 | 9 | 6 | 7 | 25:22 | 3 | 33 |
| 8 |
|
OFI Heraklion | 22 | 7 | 9 | 6 | 29:29 | 0 | 30 |
| 9 |
|
Volos NFC | 22 | 8 | 4 | 10 | 34:39 | -5 | 28 |
| 10 |
|
Panetolikos | 22 | 7 | 3 | 12 | 24:38 | -14 | 24 |
| 11 |
|
Ionikos Nikea | 22 | 5 | 6 | 11 | 21:29 | -8 | 21 |
| 12 |
|
Lamia | 22 | 4 | 6 | 12 | 18:30 | -12 | 18 |
| 13 |
|
Atromitos | 22 | 4 | 5 | 13 | 23:44 | -21 | 17 |
| 14 |
|
Apollon Smyrnis | 22 | 1 | 6 | 15 | 7:42 | -35 | 9 |
| Play-off | |
| Relégation |
