 |
 |
|
|
| 18.12.2021 | 13:45 | Apollon Pontou | - | Olympiakos Piraeus II | 0:0 (0:0) | |
| 16:00 | Veria FC | - | Panserraikos | 3:0 (1:0) | ||
| 19.12.2021 | 13:45 | Anagennisi Karditsa | - | Apollon Lárissa | 1:0 (0:0) | |
| 13:45 | Pierikos Katerini | - | AE Lárissa | 0:0 (0:0) | ||
| 13:45 | Thesprotos | - | PAOK Saloniki II | 1:1 (0:0) | ||
| 13:45 | AO Kavala | - | Olympiakos Volou | 0:5 (0:4) | ||
| 16:00 | Xanthi FC | - | AO Trikala | 5:0 (3:0) | ||
| 19.01.2022 | 14:00 | Almopos Arideas | - | Niki Volou FC | 0:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Xanthi FC | 8 | 7 | 1 | 0 | 19:1 | 18 | 22 |
| 2 |
|
Veria FC | 9 | 6 | 3 | 0 | 19:6 | 13 | 21 |
| 3 |
|
Anagennisi Karditsa | 9 | 5 | 1 | 3 | 16:8 | 8 | 16 |
| 4 |
|
Olympiakos Piraeus II | 8 | 3 | 5 | 0 | 9:5 | 4 | 14 |
| 5 |
|
Niki Volou FC | 9 | 3 | 4 | 2 | 13:5 | 8 | 13 |
| 6 |
|
Thesprotos | 8 | 4 | 1 | 3 | 12:4 | 8 | 13 |
| 7 |
|
AE Lárissa | 8 | 3 | 4 | 1 | 9:4 | 5 | 13 |
| 8 |
|
Almopos Arideas | 8 | 4 | 1 | 3 | 12:8 | 4 | 13 |
| 9 |
|
PAOK Saloniki II | 9 | 2 | 4 | 3 | 9:9 | 0 | 10 |
| 10 |
|
AO Trikala | 9 | 2 | 4 | 3 | 9:14 | -5 | 10 |
| 11 |
|
Pierikos Katerini | 9 | 2 | 3 | 4 | 10:9 | 1 | 9 |
| 12 |
|
AEP Iraklis FC | 8 | 1 | 6 | 1 | 3:4 | -1 | 9 |
| 13 |
|
Panserraikos | 8 | 2 | 3 | 3 | 8:11 | -3 | 9 |
| 14 |
|
Apollon Pontou | 9 | 2 | 2 | 5 | 12:13 | -1 | 8 |
| 15 |
|
Olympiakos Volou | 9 | 2 | 2 | 5 | 11:16 | -5 | 8 |
| 16 |
|
AO Kavala | 8 | 1 | 0 | 7 | 3:46 | -43 | 3 |
| 17 |
|
Apollon Lárissa | 8 | 0 | 2 | 6 | 6:17 | -11 | 2 |
| Play-off | |
| Relégation |
