 |
 |
|
|
| 09.03.2022 | 14:00 | Thesprotos | - | Almopos Arideas | 0:3 (0:2) | |
| 14:00 | Xanthi FC | - | Niki Volou FC | 0:0 (0:0) | ||
| 14:00 | Apollon Pontou | - | AO Trikala | 3:0 (1:0) | ||
| 14:00 | AEP Iraklis FC | - | Apollon Lárissa | 4:0 (2:0) | ||
| 14:00 | Panserraikos | - | Olympiakos Piraeus II | 4:0 (2:0) | ||
| 14:30 | Veria FC | - | AE Lárissa | 1:1 (1:1) | ||
| 10.03.2022 | 14:00 | Anagennisi Karditsa | - | PAOK Saloniki II | 1:0 (1:0) | |
| 20.04.2022 | 14:00 | Pierikos Katerini | - | Olympiakos Volou | 2:2 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Veria FC | 22 | 16 | 4 | 2 | 47:18 | 29 | 52 |
| 2 |
|
AE Lárissa | 21 | 13 | 7 | 1 | 30:7 | 23 | 46 |
| 3 |
|
Anagennisi Karditsa | 22 | 12 | 5 | 5 | 32:18 | 14 | 41 |
| 4 |
|
Xanthi FC | 21 | 9 | 9 | 3 | 30:14 | 16 | 36 |
| 5 |
|
AEP Iraklis FC | 22 | 7 | 11 | 4 | 26:16 | 10 | 32 |
| 6 |
|
Niki Volou FC | 22 | 8 | 8 | 6 | 24:14 | 10 | 32 |
| 7 |
|
PAOK Saloniki II | 22 | 8 | 8 | 6 | 27:21 | 6 | 32 |
| 8 |
|
Almopos Arideas | 22 | 8 | 6 | 8 | 31:24 | 7 | 30 |
| 9 |
|
Olympiakos Piraeus II | 21 | 7 | 7 | 7 | 23:25 | -2 | 28 |
| 10 |
|
Thesprotos | 21 | 6 | 6 | 9 | 25:24 | 1 | 24 |
| 11 |
|
Apollon Pontou | 22 | 6 | 6 | 10 | 26:31 | -5 | 24 |
| 12 |
|
Apollon Lárissa | 21 | 5 | 7 | 9 | 15:29 | -14 | 22 |
| 13 |
|
Panserraikos | 22 | 4 | 8 | 10 | 24:31 | -7 | 20 |
| 14 |
|
Pierikos Katerini | 22 | 4 | 8 | 10 | 22:33 | -11 | 20 |
| 15 |
|
AO Trikala | 22 | 5 | 5 | 12 | 16:34 | -18 | 20 |
| 16 |
|
AO Kavala | 21 | 4 | 6 | 11 | 16:61 | -45 | 18 |
| 17 |
|
Olympiakos Volou | 22 | 4 | 5 | 13 | 24:38 | -14 | 17 |
| Play-off | |
| Relégation |
