 |
 |
|
|
| 26.01.2022 | 14:00 | Panserraikos | - | Pierikos Katerini | 1:1 (1:0) | |
| 14:00 | Veria FC | - | Apollon Pontou | 5:0 (4:0) | ||
| 02.02.2022 | 14:00 | PAOK Saloniki II | - | Niki Volou FC | 2:2 (2:0) | |
| 14:00 | AO Trikala | - | Almopos Arideas | 1:0 (0:0) | ||
| 14:00 | AE Lárissa | - | AO Kavala | 3:0 (1:0) | ||
| 14:00 | Apollon Lárissa | - | Thesprotos | 2:1 (1:1) | ||
| 14:00 | Olympiakos Piraeus II | - | Xanthi FC | 1:1 (0:0) | ||
| 23.02.2022 | 14:00 | AEP Iraklis FC | - | Anagennisi Karditsa | 1:1 (1:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Veria FC | 11 | 7 | 3 | 1 | 24:7 | 17 | 24 |
| 2 |
|
Xanthi FC | 11 | 7 | 3 | 1 | 20:6 | 14 | 24 |
| 3 |
|
Anagennisi Karditsa | 12 | 7 | 2 | 3 | 19:9 | 10 | 23 |
| 4 |
|
AE Lárissa | 11 | 5 | 5 | 1 | 16:4 | 12 | 20 |
| 5 |
|
Olympiakos Piraeus II | 11 | 4 | 6 | 1 | 12:8 | 4 | 18 |
| 6 |
|
Niki Volou FC | 11 | 4 | 5 | 2 | 16:7 | 9 | 17 |
| 7 |
|
AO Trikala | 12 | 4 | 4 | 4 | 12:16 | -4 | 16 |
| 8 |
|
PAOK Saloniki II | 12 | 3 | 6 | 3 | 14:13 | 1 | 15 |
| 9 |
|
Thesprotos | 11 | 4 | 2 | 5 | 14:8 | 6 | 14 |
| 10 |
|
Almopos Arideas | 11 | 4 | 2 | 5 | 14:12 | 2 | 14 |
| 11 |
|
AEP Iraklis FC | 11 | 2 | 8 | 1 | 6:6 | 0 | 14 |
| 12 |
|
Apollon Pontou | 12 | 3 | 3 | 6 | 17:21 | -4 | 12 |
| 13 |
|
Pierikos Katerini | 12 | 2 | 5 | 5 | 12:12 | 0 | 11 |
| 14 |
|
Panserraikos | 11 | 2 | 4 | 5 | 11:17 | -6 | 10 |
| 15 |
|
Olympiakos Volou | 11 | 2 | 3 | 6 | 12:18 | -6 | 9 |
| 16 |
|
Apollon Lárissa | 11 | 1 | 4 | 6 | 8:18 | -10 | 7 |
| 17 |
|
AO Kavala | 11 | 2 | 1 | 8 | 5:50 | -45 | 7 |
| Play-off | |
| Relégation |
