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| 14.01.2022 | 20:00 | FC Rouen 1899 | - | FC Lorient B | 1:1 (0:0) | |
| 15.01.2022 | 15:00 | FC Versailles | - | St-Pryvé St-Hilaire | 3:1 (1:1) | |
| 17:00 | SO Romorantin | - | EA Guingamp B | 2:3 (2:0) | ||
| 18:00 | AS Vitré | - | Blois Foot 41 | 4:1 (2:1) | ||
| 18:00 | US Granvillaise | - | AS Poissy | 2:2 (2:1) | ||
| 29.01.2022 | 18:00 | SM Caen B | - | Châteaubriant Voltigeurs | 4:0 (1:0) | |
| 18:00 | US Saint-Malo | - | Stade Plabennec | 1:1 (1:1) | ||
| 18:30 | Vannes OC | - | C'Chartres Football | 2:3 (0:2) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Versailles | 15 | 9 | 5 | 1 | 22:9 | 13 | 32 |
| 2 |
|
FC Lorient B | 15 | 9 | 4 | 2 | 24:10 | 14 | 31 |
| 3 |
|
Châteaubriant Voltigeurs | 15 | 8 | 3 | 4 | 22:16 | 6 | 27 |
| 4 |
|
C'Chartres Football | 15 | 7 | 2 | 6 | 25:19 | 6 | 23 |
| 5 |
|
Blois Foot 41 | 15 | 6 | 5 | 4 | 21:25 | -4 | 23 |
| 6 |
|
St-Pryvé St-Hilaire | 15 | 6 | 4 | 5 | 16:15 | 1 | 22 |
| 7 |
|
EA Guingamp B | 15 | 6 | 4 | 5 | 21:21 | 0 | 22 |
| 8 |
|
Vannes OC | 15 | 5 | 6 | 4 | 20:16 | 4 | 21 |
| 9 |
|
SM Caen B | 15 | 5 | 5 | 5 | 13:16 | -3 | 20 |
| 10 |
|
FC Rouen 1899 | 15 | 4 | 6 | 5 | 17:16 | 1 | 18 |
| 11 |
|
AS Poissy | 15 | 3 | 8 | 4 | 16:15 | 1 | 17 |
| 12 |
|
US Granvillaise | 15 | 3 | 8 | 4 | 14:15 | -1 | 17 |
| 13 |
|
SO Romorantin | 15 | 4 | 4 | 7 | 15:23 | -8 | 16 |
| 14 |
|
US Saint-Malo | 15 | 3 | 4 | 8 | 9:20 | -11 | 13 |
| 15 |
|
Stade Plabennec | 15 | 2 | 4 | 9 | 11:20 | -9 | 10 |
| 16 |
|
AS Vitré | 15 | 2 | 4 | 9 | 10:20 | -10 | 10 |
| Promotion | |
| Relégation |
