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| 28.08.2021 | 15:00 | Toulouse FC | - | Valenciennes FC | 1:0 (1:0) | |
| 15:00 | Nîmes Olympique | - | SM Caen | 0:0 (0:0) | ||
| 19:00 | AS Nancy Lorraine | - | AJ Auxerre | 1:4 (0:2) | ||
| 19:00 | EA Guingamp | - | AC Ajaccio | 1:1 (0:1) | ||
| 19:00 | Chamois Niortais | - | Amiens SC | 0:0 (0:0) | ||
| 19:00 | Pau FC | - | Dijon FCO | 2:0 (1:0) | ||
| 19:00 | FC Sochaux | - | Grenoble Foot 38 | 1:0 (1:0) | ||
| 19:00 | Rodez AF | - | USL Dunkerque | 2:2 (0:1) | ||
| 19:00 | SC Bastia | - | Havre AC | 0:0 (0:0) | ||
| 19:00 | US Quevilly-Rouen | - | Paris FC | 0:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Toulouse FC | 6 | 5 | 1 | 0 | 13:4 | 9 | 16 |
| 2 |
|
Paris FC | 6 | 4 | 1 | 1 | 10:4 | 6 | 13 |
| 3 |
|
FC Sochaux | 6 | 4 | 1 | 1 | 7:4 | 3 | 13 |
| 4 |
|
Nîmes Olympique | 6 | 3 | 3 | 0 | 8:2 | 6 | 12 |
| 5 |
|
AC Ajaccio | 6 | 3 | 3 | 0 | 9:4 | 5 | 12 |
| 6 |
|
AJ Auxerre | 6 | 3 | 2 | 1 | 11:5 | 6 | 11 |
| 7 |
|
SM Caen | 6 | 3 | 1 | 2 | 7:4 | 3 | 10 |
| 8 |
|
Pau FC | 6 | 3 | 1 | 2 | 6:3 | 3 | 10 |
| 9 |
|
Havre AC | 6 | 2 | 3 | 1 | 5:3 | 2 | 9 |
| 10 |
|
Rodez AF | 6 | 2 | 3 | 1 | 8:8 | 0 | 9 |
| 11 |
|
Chamois Niortais | 6 | 2 | 2 | 2 | 4:4 | 0 | 8 |
| 12 |
|
US Quevilly-Rouen | 6 | 2 | 1 | 3 | 7:8 | -1 | 7 |
| 13 |
|
EA Guingamp | 6 | 1 | 4 | 1 | 4:5 | -1 | 7 |
| 14 |
|
SC Bastia | 6 | 1 | 3 | 2 | 4:6 | -2 | 6 |
| 15 |
|
Amiens SC | 6 | 1 | 2 | 3 | 5:8 | -3 | 5 |
| 16 |
|
Valenciennes FC | 6 | 1 | 2 | 3 | 3:9 | -6 | 5 |
| 17 |
|
Grenoble Foot 38 | 6 | 1 | 1 | 4 | 2:9 | -7 | 4 |
| 18 |
|
USL Dunkerque | 6 | 0 | 2 | 4 | 5:10 | -5 | 2 |
| 19 |
|
Dijon FCO | 6 | 0 | 1 | 5 | 6:14 | -8 | 1 |
| 20 |
|
AS Nancy Lorraine | 6 | 0 | 1 | 5 | 3:13 | -10 | 1 |
| Promotion | |
| Play-off | |
| Relégation | |
| Relégation |
