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| 16.01.2020 | 20:55 | Pau FC | - | Girondins Bordeaux | 3:2 (2:1, 2:2) ap | |
| 17.01.2020 | 21:05 | US Granvillaise | - | Olympique Marseille | 0:3 (0:0) | |
| 18.01.2020 | 13:00 | AS Prix-lès-Mézières | - | FC Limonest | 0:1 (0:0) | |
| 13:00 | SAS Épinal | - | JS Saint-Pierroise | 1:0 (0:0, 0:0) ap | ||
| 13:00 | OGC Nice | - | Red Star FC | 2:1 (2:0) | ||
| 15:00 | ASM Belfort | - | AS Nancy Lorraine | 3:1 (1:1) | ||
| 15:00 | ESM Gonfreville | - | Lille OSC | 0:2 (0:0) | ||
| 18:00 | Paris FC | - | AS Saint-Étienne | 2:3 (1:1) | ||
| 18:00 | Angoulême CFC | - | RC Strasbourg | 1:5 (1:4) | ||
| 20:55 | FC Nantes | - | Olympique Lyonnais | 3:4 (1:3) | ||
| 19.01.2020 | 17:15 | Athletico Marseille | - | Stade Rennais | 0:2 (0:2) | |
| 17:15 | Dijon FCO | - | Nîmes Olympique | 5:0 (1:0) | ||
| 17:15 | FC Rouen 1899 | - | Angers SCO | 1:4 (1:3) | ||
| 17:15 | Montpellier HSC | - | SM Caen | 5:0 (3:0) | ||
| 20:55 | FC Lorient | - | Paris Saint-Germain | 0:1 (0:0) | ||
| 20.01.2020 | 20:55 | St-Pryvé St-Hilaire | - | AS Monaco | 1:3 (0:3) |
