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| 01.05.2022 | 15:00 | SM Caen | - | US Avranches | 0:1 (0:0) | |
| 15:00 | Le Mans FC | - | AS Vitré | 2:0 (1:0) | ||
| 15:00 | Paris Saint-Germain | - | FC Rouen 1899 | 5:1 (3:1) | ||
| 15:00 | Blois Foot 41 | - | Montrouge FC | 1:1 (1:0) | ||
| 15:00 | Havre AC | - | Paris FC | 0:2 (0:0) | ||
| 15:00 | FC Mantois | - | US Orléans | 3:1 (3:0) | ||
| 15:00 | CS Brétigny | - | Tours FC | 4:3 (1:1) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Paris Saint-Germain | 25 | 17 | 4 | 4 | 76:33 | 43 | 55 |
| 2 |
|
Paris FC | 25 | 15 | 5 | 5 | 65:33 | 32 | 50 |
| 3 |
|
SM Caen | 25 | 14 | 4 | 7 | 44:30 | 14 | 46 |
| 4 |
|
US Avranches | 25 | 13 | 2 | 10 | 47:44 | 3 | 41 |
| 5 |
|
US Orléans | 25 | 12 | 4 | 9 | 50:46 | 4 | 40 |
| 6 |
|
Havre AC | 25 | 11 | 6 | 8 | 54:31 | 23 | 39 |
| 7 |
|
Montrouge FC | 25 | 10 | 9 | 6 | 39:32 | 7 | 39 |
| 8 |
|
CS Brétigny | 25 | 10 | 7 | 8 | 51:54 | -3 | 37 |
| 9 |
|
FC Mantois | 25 | 9 | 7 | 9 | 40:32 | 8 | 34 |
| 10 |
|
Le Mans FC | 25 | 7 | 5 | 13 | 36:46 | -10 | 26 |
| 11 |
|
FC Rouen 1899 | 25 | 6 | 6 | 13 | 48:60 | -12 | 24 |
| 12 |
|
Tours FC | 25 | 6 | 3 | 16 | 32:62 | -30 | 21 |
| 13 |
|
Blois Foot 41 | 25 | 5 | 5 | 15 | 32:58 | -26 | 20 |
| 14 |
|
AS Vitré | 25 | 6 | 1 | 18 | 32:85 | -53 | 19 |
| Relégation |
