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| 23.01.2022 | 14:30 | Havre AC | - | US Orléans | 1:1 (1:1) | |
| 14:30 | SM Caen | - | Valenciennes FC | 2:1 (0:1) | ||
| 14:30 | Paris Saint-Germain | - | RC Lens | 6:0 (4:0) | ||
| 14:30 | JA Drancy | - | Montfermeil FC | 2:0 (0:0) | ||
| 14:30 | Amiens SC | - | St-Pryvé St-Hilaire | 8:1 (6:1) | ||
| 14:30 | Entente Feignies Aulnoye | - | Lille OSC | 1:2 (1:2) | ||
| 14:30 | FC Chambly | - | Évreux FC 27 | 1:0 (0:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Paris Saint-Germain | 16 | 14 | 1 | 1 | 58:14 | 44 | 43 |
| 2 |
|
JA Drancy | 16 | 10 | 3 | 3 | 31:19 | 12 | 33 |
| 3 |
|
Amiens SC | 16 | 9 | 2 | 5 | 34:20 | 14 | 29 |
| 4 |
|
SM Caen | 16 | 8 | 3 | 5 | 34:28 | 6 | 27 |
| 5 |
|
Lille OSC | 16 | 7 | 4 | 5 | 27:22 | 5 | 25 |
| 6 |
|
Valenciennes FC | 16 | 8 | 1 | 7 | 20:23 | -3 | 25 |
| 7 |
|
US Orléans | 16 | 7 | 3 | 6 | 28:24 | 4 | 24 |
| 8 |
|
Havre AC | 16 | 5 | 7 | 4 | 25:23 | 2 | 22 |
| 9 |
|
RC Lens | 16 | 5 | 5 | 6 | 20:27 | -7 | 20 |
| 10 |
|
Montfermeil FC | 16 | 6 | 1 | 9 | 18:22 | -4 | 19 |
| 11 |
|
Entente Feignies Aulnoye | 16 | 5 | 2 | 9 | 23:26 | -3 | 17 |
| 12 |
|
FC Chambly | 16 | 3 | 5 | 8 | 17:24 | -7 | 14 |
| 13 |
|
Évreux FC 27 | 16 | 3 | 3 | 10 | 18:35 | -17 | 12 |
| 14 |
|
St-Pryvé St-Hilaire | 16 | 2 | 0 | 14 | 8:54 | -46 | 6 |
| Play-off | |
| Relégation |
