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| 07.05.2023 | 12:00 | Real Betis B | - | CD El Ejido 2012 | 1:2 (0:1) | |
| 12:00 | Cádiz CF B | - | Utrera CD | 2:1 (0:1) | ||
| 12:00 | Atlético Mancha Real | - | Recreativo Huelva | 0:1 (0:1) | ||
| 12:00 | CD San Roque de Lepe | - | Recreativo Granada | 1:2 (0:2) | ||
| 12:00 | Atlético Sanluqueño CF | - | Antequera CF | 4:2 (1:2) | ||
| 12:00 | Juventud Torremolinos | - | Sevilla Atlético | 0:2 (0:2) | ||
| 12:00 | UCAM Murcia CF | - | Mar Menor CF | 3:0 (1:0) | ||
| 12:00 | Vélez CF | - | Xerez DFC | 1:1 (0:1) | ||
| 12:00 | Yeclano Deportivo | - | FC Cartagena B | 0:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Antequera CF | 33 | 22 | 7 | 4 | 58:23 | 35 | 73 |
| 2 |
|
Recreativo Huelva | 33 | 17 | 11 | 5 | 38:23 | 15 | 62 |
| 3 |
|
Recreativo Granada | 33 | 16 | 8 | 9 | 45:31 | 14 | 56 |
| 4 |
|
Atlético Sanluqueño CF | 33 | 15 | 10 | 8 | 45:32 | 13 | 55 |
| 5 |
|
UCAM Murcia CF | 33 | 13 | 14 | 6 | 45:26 | 19 | 53 |
| 6 |
|
Yeclano Deportivo | 33 | 13 | 12 | 8 | 35:29 | 6 | 51 |
| 7 |
|
CD San Roque de Lepe | 33 | 12 | 10 | 11 | 34:29 | 5 | 46 |
| 8 |
|
Real Betis B | 33 | 11 | 11 | 11 | 33:33 | 0 | 44 |
| 9 |
|
Mar Menor CF | 33 | 12 | 8 | 13 | 32:36 | -4 | 44 |
| 10 |
|
FC Cartagena B | 33 | 12 | 8 | 13 | 37:41 | -4 | 44 |
| 11 |
|
Sevilla Atlético | 33 | 12 | 6 | 15 | 33:30 | 3 | 42 |
| 12 |
|
Cádiz CF B | 33 | 11 | 9 | 13 | 37:46 | -9 | 42 |
| 13 |
|
Vélez CF | 33 | 12 | 5 | 16 | 37:50 | -13 | 41 |
| 14 |
|
CD El Ejido 2012 | 33 | 11 | 6 | 16 | 33:39 | -6 | 39 |
| 15 |
|
Xerez DFC | 33 | 9 | 10 | 14 | 27:35 | -8 | 37 |
| 16 |
|
Juventud Torremolinos | 33 | 8 | 10 | 15 | 29:37 | -8 | 34 |
| 17 |
|
Atlético Mancha Real | 33 | 8 | 7 | 18 | 25:45 | -20 | 31 |
| 18 |
|
Utrera CD | 33 | 5 | 4 | 24 | 25:63 | -38 | 19 |
| Promotion | |
| Play-off | |
| Relégation |
