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| 29.01.2023 | 12:00 | Utrera CD | - | Juventud Torremolinos | 1:2 (1:2) | |
| 12:00 | FC Cartagena B | - | Atlético Sanluqueño CF | 2:1 (1:1) | ||
| 12:00 | Recreativo Granada | - | Cádiz CF B | 2:0 (1:0) | ||
| 12:00 | Vélez CF | - | Atlético Mancha Real | 1:0 (0:0) | ||
| 17:00 | CD El Ejido 2012 | - | Antequera CF | 0:2 (0:1) | ||
| 17:00 | Sevilla Atlético | - | Yeclano Deportivo | 2:1 (0:0) | ||
| 17:00 | Recreativo Huelva | - | CD San Roque de Lepe | 1:1 (0:1) | ||
| 17:00 | Mar Menor CF | - | Real Betis B | 1:0 (0:0) | ||
| 17:00 | Xerez DFC | - | UCAM Murcia CF | 1:2 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Antequera CF | 19 | 15 | 3 | 1 | 39:13 | 26 | 48 |
| 2 |
|
Recreativo Huelva | 19 | 10 | 6 | 3 | 25:16 | 9 | 36 |
| 3 |
|
Atlético Sanluqueño CF | 19 | 8 | 6 | 5 | 25:20 | 5 | 30 |
| 4 |
|
Vélez CF | 19 | 9 | 3 | 7 | 21:21 | 0 | 30 |
| 5 |
|
UCAM Murcia CF | 19 | 7 | 7 | 5 | 26:20 | 6 | 28 |
| 6 |
|
Recreativo Granada | 19 | 8 | 4 | 7 | 25:20 | 5 | 28 |
| 7 |
|
Yeclano Deportivo | 19 | 7 | 7 | 5 | 19:16 | 3 | 28 |
| 8 |
|
Mar Menor CF | 19 | 7 | 7 | 5 | 20:17 | 3 | 28 |
| 9 |
|
FC Cartagena B | 19 | 8 | 3 | 8 | 20:24 | -4 | 27 |
| 10 |
|
Atlético Mancha Real | 19 | 7 | 4 | 8 | 15:22 | -7 | 25 |
| 11 |
|
Real Betis B | 19 | 6 | 6 | 7 | 16:19 | -3 | 24 |
| 12 |
|
CD San Roque de Lepe | 19 | 6 | 5 | 8 | 21:20 | 1 | 23 |
| 13 |
|
Xerez DFC | 19 | 5 | 6 | 8 | 16:20 | -4 | 21 |
| 14 |
|
Cádiz CF B | 19 | 5 | 6 | 8 | 21:26 | -5 | 21 |
| 15 |
|
Juventud Torremolinos | 19 | 4 | 8 | 7 | 15:20 | -5 | 20 |
| 16 |
|
CD El Ejido 2012 | 19 | 5 | 4 | 10 | 15:22 | -7 | 19 |
| 17 |
|
Sevilla Atlético | 19 | 5 | 2 | 12 | 19:24 | -5 | 17 |
| 18 |
|
Utrera CD | 19 | 4 | 3 | 12 | 16:34 | -18 | 15 |
| Promotion | |
| Play-off | |
| Relégation |
