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| 03.12.2017 | 12:00 | UD Melilla | - | Marbella FC | 1:2 (0:1) | |
| 12:00 | Recreativo Huelva | - | Granada CF B | 0:0 (0:0) | ||
| 12:00 | Écija Balompié | - | UD Las Palmas B | 0:3 (0:1) | ||
| 12:00 | Real Betis B | - | Real Murcia | 0:0 (0:0) | ||
| 17:00 | CF Villanovense | - | Mérida AD | 0:0 (0:0) | ||
| 17:00 | CD El Ejido 2012 | - | San Fernando CD | 1:1 (1:1) | ||
| 17:00 | RB Linense | - | FC Jumilla | 1:1 (0:0) | ||
| 17:00 | Lorca Deportiva | - | FC Cartagena | 1:2 (1:0) | ||
| 17:00 | Extremadura UD | - | CD Badajoz | 5:2 (4:0) | ||
| 17:30 | UCAM Murcia CF | - | Córdoba CF B | 2:1 (2:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Cartagena | 17 | 8 | 6 | 3 | 23:18 | 5 | 30 |
| 2 |
|
Marbella FC | 17 | 9 | 3 | 5 | 18:14 | 4 | 30 |
| 3 |
|
Extremadura UD | 17 | 8 | 5 | 4 | 23:14 | 9 | 29 |
| 4 |
|
Granada CF B | 17 | 7 | 6 | 4 | 18:14 | 4 | 27 |
| 5 |
|
UCAM Murcia CF | 17 | 7 | 6 | 4 | 16:15 | 1 | 27 |
| 6 |
|
Real Murcia | 17 | 7 | 5 | 5 | 23:16 | 7 | 26 |
| 7 |
|
RB Linense | 17 | 6 | 7 | 4 | 23:16 | 7 | 25 |
| 8 |
|
CF Villanovense | 17 | 6 | 7 | 4 | 15:13 | 2 | 25 |
| 9 |
|
Recreativo Huelva | 17 | 6 | 7 | 4 | 15:12 | 3 | 25 |
| 10 |
|
Mérida AD | 17 | 6 | 6 | 5 | 19:16 | 3 | 24 |
| 11 |
|
Écija Balompié | 17 | 6 | 6 | 5 | 21:25 | -4 | 24 |
| 12 |
|
San Fernando CD | 17 | 6 | 5 | 6 | 24:22 | 2 | 23 |
| 13 |
|
CD El Ejido 2012 | 17 | 5 | 7 | 5 | 24:24 | 0 | 22 |
| 14 |
|
UD Melilla | 17 | 6 | 4 | 7 | 14:12 | 2 | 22 |
| 15 |
|
Córdoba CF B | 17 | 4 | 7 | 6 | 22:21 | 1 | 19 |
| 16 |
|
Real Betis B | 17 | 4 | 7 | 6 | 20:23 | -3 | 19 |
| 17 |
|
CD Badajoz | 17 | 3 | 8 | 6 | 17:22 | -5 | 17 |
| 18 |
|
FC Jumilla | 17 | 3 | 7 | 7 | 15:21 | -6 | 16 |
| 19 |
|
Lorca Deportiva | 17 | 2 | 5 | 10 | 14:35 | -21 | 11 |
| 20 |
|
UD Las Palmas B | 17 | 2 | 4 | 11 | 16:27 | -11 | 10 |
| Play-off | |
| Play-off | |
| Relégation | |
| Relégation |
