 |
 |
|
| 12.02.2022 | 17:00 | FC Barcelona B | - | Linares Deportivo | 1:1 (0:0) | |
| 19:00 | Atlético Sanluqueño CF | - | CE Sabadell | 0:3 (0:2) | ||
| 13.02.2022 | 12:00 | FC Andorra | - | Villarreal CF B | 0:1 (0:1) | |
| 12:00 | CD Alcoyano | - | Sevilla Atlético | 2:1 (2:1) | ||
| 12:00 | Real Betis B | - | Atlético Baleares | 0:2 (0:1) | ||
| 12:00 | RB Linense | - | UE Costa Brava | 0:0 (0:0) | ||
| 17:00 | Gimnàstic de Tarragona | - | Algeciras CF | 1:0 (1:0) | ||
| 17:00 | CD Castellón | - | San Fernando CD | 1:3 (0:3) | ||
| 17:00 | Albacete | - | UE Cornellà | 3:0 (1:0) | ||
| 30.03.2022 | 20:30 | Real Madrid Castilla | - | UCAM Murcia CF | 3:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Villarreal CF B | 23 | 14 | 2 | 7 | 40:21 | 19 | 44 |
| 2 |
|
Albacete | 23 | 13 | 5 | 5 | 31:20 | 11 | 44 |
| 3 |
|
FC Andorra | 23 | 12 | 5 | 6 | 35:20 | 15 | 41 |
| 4 |
|
Atlético Baleares | 23 | 11 | 6 | 6 | 31:22 | 9 | 39 |
| 5 |
|
CD Alcoyano | 23 | 9 | 8 | 6 | 26:23 | 3 | 35 |
| 6 |
|
CD Castellón | 23 | 10 | 5 | 8 | 25:25 | 0 | 35 |
| 7 |
|
Gimnàstic de Tarragona | 23 | 9 | 7 | 7 | 20:18 | 2 | 34 |
| 8 |
|
San Fernando CD | 23 | 10 | 4 | 9 | 31:30 | 1 | 34 |
| 9 |
|
Algeciras CF | 23 | 9 | 6 | 8 | 33:28 | 5 | 33 |
| 10 |
|
Real Madrid Castilla | 23 | 9 | 5 | 9 | 32:25 | 7 | 32 |
| 11 |
|
RB Linense | 23 | 8 | 8 | 7 | 19:23 | -4 | 32 |
| 12 |
|
Sevilla Atlético | 23 | 9 | 4 | 10 | 23:34 | -11 | 31 |
| 13 |
|
CE Sabadell | 23 | 7 | 9 | 7 | 22:21 | 1 | 30 |
| 14 |
|
FC Barcelona B | 23 | 7 | 8 | 8 | 28:28 | 0 | 29 |
| 15 |
|
Atlético Sanluqueño CF | 23 | 8 | 5 | 10 | 24:29 | -5 | 29 |
| 16 |
|
UE Cornellà | 23 | 9 | 2 | 12 | 24:29 | -5 | 29 |
| 17 |
|
Linares Deportivo | 23 | 7 | 7 | 9 | 29:29 | 0 | 28 |
| 18 |
|
UCAM Murcia CF | 23 | 6 | 5 | 12 | 26:33 | -7 | 23 |
| 19 |
|
UE Costa Brava | 23 | 3 | 10 | 10 | 12:28 | -16 | 19 |
| 20 |
|
Real Betis B | 23 | 3 | 3 | 17 | 12:37 | -25 | 12 |
| Promotion | |
| Play-off | |
| Relégation |
