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|
| 29.01.2022 | 17:00 | RC Celta B | - | Athletic Club B | 4:1 (2:0) | |
| 19:00 | Cultural Leonesa | - | CD Badajoz | 1:0 (0:0) | ||
| 19:00 | SD Logroñés | - | Unionistas CF | 1:0 (0:0) | ||
| 30.01.2022 | 12:00 | CD Calahorra | - | Zamora CF | 0:0 (0:0) | |
| 12:00 | UD SS Reyes | - | UD Logroñés | 1:1 (0:0) | ||
| 12:00 | Inter de Madrid | - | Extremadura UD | 4:2 (2:2) | ||
| 17:00 | CF Talavera | - | CD Tudelano | 2:1 (1:0) | ||
| 16.02.2022 | 20:30 | Deportivo La Coruña | - | Racing Santander | 0:1 (0:1) | |
| 02.03.2022 | 19:00 | Real Unión | - | Real Valladolid B | 2:1 (1:1) | |
| 08.03.2022 | 20:30 | Racing Ferrol | - | Rayo Majadahonda | 2:1 (1:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Deportivo La Coruña | 21 | 14 | 4 | 3 | 33:12 | 21 | 46 |
| 2 |
|
Racing Santander | 21 | 13 | 4 | 4 | 30:17 | 13 | 43 |
| 3 |
|
Real Unión | 21 | 11 | 3 | 7 | 30:23 | 7 | 36 |
| 4 |
|
UD Logroñés | 21 | 10 | 5 | 6 | 21:20 | 1 | 35 |
| 5 |
|
Unionistas CF | 21 | 8 | 11 | 2 | 31:18 | 13 | 35 |
| 6 |
|
Rayo Majadahonda | 21 | 10 | 4 | 7 | 26:21 | 5 | 34 |
| 7 |
|
RC Celta B | 21 | 10 | 4 | 7 | 32:25 | 7 | 34 |
| 8 |
|
Racing Ferrol | 21 | 9 | 5 | 7 | 24:16 | 8 | 32 |
| 9 |
|
SD Logroñés | 21 | 7 | 8 | 6 | 26:22 | 4 | 29 |
| 10 |
|
Cultural Leonesa | 21 | 7 | 8 | 6 | 32:29 | 3 | 29 |
| 11 |
|
CD Badajoz | 21 | 7 | 8 | 6 | 22:19 | 3 | 29 |
| 12 |
|
UD SS Reyes | 21 | 8 | 5 | 8 | 21:27 | -6 | 29 |
| 13 |
|
CD Calahorra | 21 | 7 | 7 | 7 | 22:21 | 1 | 28 |
| 14 |
|
Inter de Madrid | 21 | 6 | 7 | 8 | 29:31 | -2 | 25 |
| 15 |
|
CF Talavera | 21 | 6 | 5 | 10 | 19:27 | -8 | 23 |
| 16 |
|
Zamora CF | 21 | 5 | 5 | 11 | 16:28 | -12 | 20 |
| 17 |
|
Athletic Club B | 21 | 3 | 8 | 10 | 19:30 | -11 | 17 |
| 18 |
|
Real Valladolid B | 21 | 4 | 5 | 12 | 24:37 | -13 | 17 |
| 19 |
|
CD Tudelano | 21 | 2 | 5 | 14 | 13:31 | -18 | 11 |
| 20 |
|
Extremadura UD | 21 | 5 | 5 | 11 | 20:36 | -16 | 0 |
| Promotion | |
| Play-off | |
| Relégation |
