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| 16.05.2021 | 13:00 | Brighton & Hove Albion WFC | - | Huddersfield Town LFC | 6:0 (3:0) | |
| 13:00 | Blackburn Rovers WFC | - | Charlton Athletic WFC | 0:1 (0:0) | ||
| 13:00 | Manchester United WFC | - | Leicester City WFC | 2:3 (1:1) | ||
| 13:30 | Birmingham City WFC | - | Southampton FC Women | 3:2 (1:0) | ||
| 15:00 | Manchester City WFC | - | West Ham United WFC | 5:1 | ||
| 15:00 | Tottenham Hotspur WFC | - | Sheffield United LFC | 2:1 ap | ||
| 16:00 | Arsenal WFC | - | Crystal Palace Women | 9:0 | ||
| 20.05.2021 | 20:00 | Chelsea FC Women | - | Everton FC | 3:0 |
