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| 11.12.2020 | 18:30 | Baník Ostrava | - | Bohemians Praha 1905 | 1:0 (1:0) | |
| 12.12.2020 | 14:00 | Dynamo České Budějovice | - | MFK Karviná | 1:1 (0:1) | |
| 14:00 | 1. FK Příbram | - | FC Fastav Zlín | 1:0 (0:0) | ||
| 14:00 | SFC Opava | - | FK Mladá Boleslav | 2:2 (2:1) | ||
| 16:00 | FK Pardubice | - | Zbrojovka Brno | 2:1 (0:0) | ||
| 16:00 | FK Teplice | - | Sigma Olomouc | 1:1 (0:1) | ||
| 18:30 | FK Jablonec | - | Viktoria Plzeň | 3:2 (0:2) | ||
| 13.12.2020 | 16:00 | 1. FC Slovácko | - | AC Sparta Praha | 1:2 (1:1) | |
| 18:30 | Slavia Praha | - | Slovan Liberec | 3:0 (2:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slavia Praha | 11 | 9 | 2 | 0 | 33:3 | 30 | 29 |
| 2 |
|
AC Sparta Praha | 11 | 8 | 0 | 3 | 26:17 | 9 | 24 |
| 3 |
|
FK Jablonec | 11 | 7 | 1 | 3 | 19:11 | 8 | 22 |
| 4 |
|
Sigma Olomouc | 11 | 5 | 5 | 1 | 17:10 | 7 | 20 |
| 5 |
|
1. FC Slovácko | 11 | 5 | 3 | 3 | 17:12 | 5 | 18 |
| 6 |
|
FK Pardubice | 11 | 5 | 3 | 3 | 13:13 | 0 | 18 |
| 7 |
|
Viktoria Plzeň | 11 | 5 | 2 | 4 | 21:16 | 5 | 17 |
| 8 |
|
Baník Ostrava | 11 | 5 | 2 | 4 | 15:10 | 5 | 17 |
| 9 |
|
MFK Karviná | 11 | 4 | 4 | 3 | 11:14 | -3 | 16 |
| 10 |
|
FC Fastav Zlín | 11 | 5 | 0 | 6 | 13:14 | -1 | 15 |
| 11 |
|
Slovan Liberec | 11 | 4 | 2 | 5 | 14:15 | -1 | 14 |
| 12 |
|
Dynamo České Budějovice | 11 | 3 | 5 | 3 | 15:19 | -4 | 14 |
| 13 |
|
Bohemians Praha 1905 | 11 | 3 | 2 | 6 | 13:15 | -2 | 11 |
| 14 |
|
FK Teplice | 11 | 3 | 1 | 7 | 12:19 | -7 | 10 |
| 15 |
|
FK Mladá Boleslav | 11 | 2 | 3 | 6 | 13:19 | -6 | 9 |
| 16 |
|
1. FK Příbram | 11 | 2 | 3 | 6 | 9:25 | -16 | 9 |
| 17 |
|
Zbrojovka Brno | 11 | 1 | 3 | 7 | 10:24 | -14 | 6 |
| 18 |
|
SFC Opava | 11 | 1 | 3 | 7 | 10:25 | -15 | 6 |
| Champions League Quali. | |
| Europa League Quali. | |
| Relégation |
