 |
 |
|
|
| 15.10.2021 | 17:30 | Huachipato | - | Antofagasta | 0:1 (0:1) | |
| 21:00 | Palestino | - | O'Higgins | 2:2 (1:1) | ||
| 23:30 | Universidad de Chile | - | Audax Italiano | 0:1 (0:1) | ||
| 16.10.2021 | 02:00 | Ñublense | - | Unión La Calera | 0:2 (0:1) | |
| 16:00 | Cobresal | - | Universidad Católica | 1:3 (1:1) | ||
| 20:00 | Santiago Wanderers | - | Everton | 2:1 (1:1) | ||
| 22:30 | Unión Española | - | Curicó Unido | 2:1 (1:0) | ||
| 17.10.2021 | 01:00 | Deportes Melipilla | - | La Serena | 1:1 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Colo-Colo | 24 | 15 | 4 | 5 | 39:20 | 19 | 49 |
| 2 |
|
Universidad Católica | 24 | 15 | 2 | 7 | 46:29 | 17 | 47 |
| 3 |
|
Audax Italiano | 25 | 12 | 8 | 5 | 32:24 | 8 | 44 |
| 4 |
|
Unión La Calera | 24 | 13 | 5 | 6 | 30:25 | 5 | 44 |
| 5 |
|
Unión Española | 25 | 12 | 3 | 10 | 40:36 | 4 | 39 |
| 6 |
|
Antofagasta | 24 | 9 | 8 | 7 | 29:29 | 0 | 35 |
| 7 |
|
Universidad de Chile | 24 | 9 | 7 | 8 | 30:27 | 3 | 34 |
| 8 |
|
Everton | 24 | 9 | 7 | 8 | 21:21 | 0 | 34 |
| 9 |
|
La Serena | 25 | 8 | 8 | 9 | 32:30 | 2 | 32 |
| 10 |
|
Cobresal | 25 | 9 | 5 | 11 | 31:29 | 2 | 32 |
| 11 |
|
Ñublense | 25 | 7 | 9 | 9 | 32:31 | 1 | 30 |
| 12 |
|
Palestino | 24 | 8 | 5 | 11 | 35:37 | -2 | 29 |
| 13 |
|
O'Higgins | 25 | 7 | 8 | 10 | 23:33 | -10 | 29 |
| 14 |
|
Curicó Unido | 25 | 6 | 9 | 10 | 29:33 | -4 | 27 |
| 15 |
|
Huachipato | 24 | 4 | 11 | 9 | 26:35 | -9 | 23 |
| 16 |
|
Deportes Melipilla | 25 | 5 | 8 | 12 | 27:43 | -16 | 23 |
| 17 |
|
Santiago Wanderers | 24 | 5 | 3 | 16 | 19:39 | -20 | 18 |
| Copa Libertadores | |
| Qualification | |
| Copa Sudamericana | |
| Relégation | |
| Relégation |
