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| H (Match allé) | Deportes Melipilla | - | Puerto Montt | 2:2 (0:0) | ||
| R (match retour) | Puerto Montt | - | Deportes Melipilla | 0:1 (0:1) | ||
| H (Match allé): 20.01.2021 23:00 | R (match retour): 24.01.2021 14:30 | vainqueur: Deportes Melipilla | ||||
| H (Match allé) | Deportes Temuco | - | Rangers | 0:1 (0:1) | ||
| R (match retour) | Rangers | - | Deportes Temuco | 1:0 (0:0) | ||
| H (Match allé): 21.01.2021 22:30 | R (match retour): 25.01.2021 01:30 | vainqueur: Rangers | ||||
