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| 21.10.2022 | 20:30 | 1. FSV Mainz 05 | - | 1. FC Köln | 5:0 (3:0) | |
| 22.10.2022 | 15:30 | Borussia Dortmund | - | VfB Stuttgart | 5:0 (3:0) | |
| 15:30 | Bayer Leverkusen | - | VfL Wolfsburg | 2:2 (1:1) | ||
| 15:30 | SC Freiburg | - | Werder Bremen | 2:0 (0:0) | ||
| 15:30 | 1899 Hoffenheim | - | Bayern München | 0:2 (0:2) | ||
| 15:30 | FC Augsburg | - | RB Leipzig | 3:3 (1:0) | ||
| 18:30 | Bor. Mönchengladbach | - | Eintracht Frankfurt | 1:3 (0:3) | ||
| 23.10.2022 | 15:30 | VfL Bochum | - | 1. FC Union Berlin | 2:1 (1:0) | |
| 17:30 | Hertha BSC | - | FC Schalke 04 | 2:1 (0:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Union Berlin | 11 | 7 | 2 | 2 | 19:8 | 11 | 23 |
| 2 |
|
Bayern München (M) | 11 | 6 | 4 | 1 | 32:8 | 24 | 22 |
| 3 |
|
SC Freiburg | 11 | 6 | 3 | 2 | 16:13 | 3 | 21 |
| 4 |
|
Eintracht Frankfurt | 11 | 6 | 2 | 3 | 24:18 | 6 | 20 |
| 5 |
|
Borussia Dortmund | 11 | 6 | 1 | 4 | 18:14 | 4 | 19 |
| 6 |
|
1. FSV Mainz 05 | 11 | 5 | 3 | 3 | 16:13 | 3 | 18 |
| 7 |
|
1899 Hoffenheim | 11 | 5 | 2 | 4 | 17:12 | 5 | 17 |
| 8 |
|
RB Leipzig (P) | 11 | 4 | 4 | 3 | 20:18 | 2 | 16 |
| 9 |
|
Bor. Mönchengladbach | 11 | 4 | 4 | 3 | 19:17 | 2 | 16 |
| 10 |
|
1. FC Köln | 11 | 4 | 4 | 3 | 19:22 | -3 | 16 |
| 11 |
|
Werder Bremen (N) | 11 | 4 | 3 | 4 | 20:18 | 2 | 15 |
| 12 |
|
FC Augsburg | 11 | 4 | 2 | 5 | 14:19 | -5 | 14 |
| 13 |
|
Hertha BSC | 11 | 2 | 5 | 4 | 14:16 | -2 | 11 |
| 14 |
|
VfL Wolfsburg | 11 | 2 | 5 | 4 | 13:19 | -6 | 11 |
| 15 |
|
Bayer Leverkusen | 11 | 2 | 3 | 6 | 16:23 | -7 | 9 |
| 16 |
|
VfB Stuttgart | 11 | 1 | 5 | 5 | 13:20 | -7 | 8 |
| 17 |
|
VfL Bochum | 11 | 2 | 1 | 8 | 11:28 | -17 | 7 |
| 18 |
|
FC Schalke 04 (N) | 11 | 1 | 3 | 7 | 11:26 | -15 | 6 |
| Champions League | |
| Europa League | |
| Relégation | |
| Relégation |
