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| 03.03.2022 | 20:00 | Royal Pari | - | Universitario de Vinto | 2:1 (1:1) | |
| 04.03.2022 | 00:30 | Oriente Petrolero | - | Universitario de Sucre | 1:0 (0:0) | |
| 05.03.2022 | 20:00 | Atlético Palmaflor | - | CD Guabirá | 1:0 (1:0) | |
| 22:15 | The Strongest | - | Nacional Potosí | 1:1 (0:0) | ||
| 06.03.2022 | 00:30 | Real Tomayapo | - | Bolívar | 1:1 (1:1) | |
| 20:00 | Real Santa Cruz | - | Club Aurora | 2:2 (1:1) | ||
| 20:00 | Always Ready | - | Jorge Wilstermann | 0:0 (0:0) | ||
| 22:15 | Independiente Petrolero | - | Blooming | 2:3 (1:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| 1 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
The Strongest | 5 | 3 | 2 | 0 | 9:3 | 6 | 11 |
| 2 |
|
Atlético Palmaflor | 5 | 3 | 1 | 1 | 6:6 | 0 | 10 |
| 3 |
|
Oriente Petrolero | 5 | 3 | 0 | 2 | 6:5 | 1 | 9 |
| 4 |
|
Nacional Potosí | 5 | 2 | 2 | 1 | 9:7 | 2 | 8 |
| 5 |
|
Universitario de Sucre | 5 | 2 | 2 | 1 | 7:6 | 1 | 8 |
| 6 |
|
Club Aurora | 5 | 0 | 3 | 2 | 4:7 | -3 | 3 |
| 7 |
|
Real Santa Cruz | 5 | 0 | 2 | 3 | 5:8 | -3 | 2 |
| 8 |
|
CD Guabirá | 5 | 0 | 2 | 3 | 4:8 | -4 | 2 |
| 2 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Bolívar | 5 | 3 | 1 | 1 | 13:2 | 11 | 10 |
| 2 |
|
Blooming | 5 | 3 | 1 | 1 | 10:10 | 0 | 10 |
| 3 |
|
Real Tomayapo | 5 | 2 | 3 | 0 | 5:3 | 2 | 9 |
| 4 |
|
Jorge Wilstermann | 5 | 2 | 1 | 2 | 3:3 | 0 | 7 |
| 5 |
|
Royal Pari | 5 | 1 | 2 | 2 | 5:7 | -2 | 5 |
| 6 |
|
Always Ready | 5 | 1 | 2 | 2 | 4:7 | -3 | 5 |
| 7 |
|
Independiente Petrolero | 5 | 1 | 1 | 3 | 5:7 | -2 | 4 |
| 8 |
|
Universitario de Vinto | 5 | 1 | 1 | 3 | 4:10 | -6 | 4 |
| Play-off | |
| Play-off |
