 |
 |
|
|
| 25.09.2021 | 23:00 | Club San José | - | Blooming | 1:2 (1:1) | |
| 26.09.2021 | 21:00 | Nacional Potosí | - | Real Potosí | 4:2 (3:0) | |
| 23:15 | Real Tomayapo | - | Bolívar | 1:3 (0:1) | ||
| 27.09.2021 | 01:30 | The Strongest | - | Always Ready | 1:1 (1:1) | |
| 21:00 | Real Santa Cruz | - | CD Guabirá | 3:0 (0:0) | ||
| 23:15 | Independiente Petrolero | - | Club Aurora | 3:0 (1:0) | ||
| 28.09.2021 | 02:00 | Oriente Petrolero | - | Royal Pari | 2:4 (2:1) | |
| 02:00 | Jorge Wilstermann | - | Atlético Palmaflor | 5:0 (2:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Always Ready | 21 | 14 | 4 | 3 | 46:19 | 27 | 46 |
| 2 |
|
Independiente Petrolero | 21 | 14 | 3 | 4 | 39:25 | 14 | 45 |
| 3 |
|
The Strongest | 21 | 13 | 4 | 4 | 47:22 | 25 | 43 |
| 4 |
|
Royal Pari | 21 | 13 | 2 | 6 | 48:27 | 21 | 41 |
| 5 |
|
Bolívar | 21 | 10 | 7 | 4 | 43:21 | 22 | 37 |
| 6 |
|
Oriente Petrolero | 21 | 10 | 5 | 6 | 32:20 | 12 | 35 |
| 7 |
|
CD Guabirá | 21 | 9 | 4 | 8 | 32:29 | 3 | 31 |
| 8 |
|
Atlético Palmaflor | 21 | 9 | 4 | 8 | 30:31 | -1 | 31 |
| 9 |
|
Jorge Wilstermann | 21 | 10 | 0 | 11 | 46:41 | 5 | 30 |
| 10 |
|
Real Santa Cruz | 21 | 8 | 4 | 9 | 30:31 | -1 | 28 |
| 11 |
|
Nacional Potosí | 21 | 7 | 7 | 7 | 28:32 | -4 | 28 |
| 12 |
|
Club Aurora | 21 | 7 | 4 | 10 | 24:34 | -10 | 25 |
| 13 |
|
Real Tomayapo | 21 | 6 | 3 | 12 | 18:32 | -14 | 21 |
| 14 |
|
Blooming | 21 | 5 | 3 | 13 | 22:37 | -15 | 18 |
| 15 |
|
Real Potosí | 21 | 4 | 3 | 14 | 21:43 | -22 | 15 |
| 16 |
|
Club San José | 21 | 0 | 1 | 20 | 5:67 | -62 | 1 |
| Copa Libertadores | |
| Copa Sudamericana | |
| Relégation | |
| Relégation |
