 |
 |
|
|
| 28.01.2022 | 20:45 | Sint-Truidense VV | - | Sporting Charleroi | 0:1 (0:1) | |
| 29.01.2022 | 16:15 | K Beerschot VA | - | SV Zulte Waregem | 3:3 (1:3) | |
| 18:30 | RFC Seraing | - | KAS Eupen | 0:0 (0:0) | ||
| 20:45 | Cercle Brugge | - | KV Oostende | 0:1 (0:0) | ||
| 30.01.2022 | 13:30 | Union Saint-Gilloise | - | RSC Anderlecht | 1:0 (1:0) | |
| 16:00 | KAA Gent | - | Royal Antwerp FC | 0:1 (0:1) | ||
| 18:30 | Standard Liège | - | KV Mechelen | 1:2 (1:0) | ||
| 21:00 | KV Kortrijk | - | Club Brugge KV | 0:1 (0:0) | ||
| 09.02.2022 | 21:00 | Oud-Heverlee Leuven | - | KRC Genk | 2:1 (1:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Union Saint-Gilloise | 25 | 18 | 3 | 4 | 57:21 | 36 | 57 |
| 2 |
|
Royal Antwerp FC | 25 | 15 | 5 | 5 | 46:26 | 20 | 50 |
| 3 |
|
Club Brugge KV | 25 | 13 | 9 | 3 | 46:30 | 16 | 48 |
| 4 |
|
RSC Anderlecht | 25 | 11 | 9 | 5 | 52:30 | 22 | 42 |
| 5 |
|
Sporting Charleroi | 25 | 11 | 7 | 7 | 40:33 | 7 | 40 |
| 6 |
|
KAA Gent | 25 | 10 | 7 | 8 | 36:26 | 10 | 37 |
| 7 |
|
KV Mechelen | 25 | 11 | 3 | 11 | 40:48 | -8 | 36 |
| 8 |
|
KRC Genk | 25 | 10 | 5 | 10 | 50:39 | 11 | 35 |
| 9 |
|
Cercle Brugge | 25 | 10 | 4 | 11 | 35:30 | 5 | 34 |
| 10 |
|
KV Kortrijk | 25 | 8 | 10 | 7 | 30:29 | 1 | 34 |
| 11 |
|
Oud-Heverlee Leuven | 25 | 8 | 9 | 8 | 38:39 | -1 | 33 |
| 12 |
|
Standard Liège | 25 | 8 | 7 | 10 | 29:39 | -10 | 31 |
| 13 |
|
Sint-Truidense VV | 25 | 8 | 4 | 13 | 26:36 | -10 | 28 |
| 14 |
|
KV Oostende | 25 | 8 | 4 | 13 | 26:46 | -20 | 28 |
| 15 |
|
KAS Eupen | 25 | 7 | 6 | 12 | 31:41 | -10 | 27 |
| 16 |
|
SV Zulte Waregem | 25 | 6 | 8 | 11 | 36:52 | -16 | 26 |
| 17 |
|
RFC Seraing | 25 | 7 | 2 | 16 | 26:50 | -24 | 23 |
| 18 |
|
K Beerschot VA | 25 | 3 | 4 | 18 | 23:52 | -29 | 13 |
| Play-off | |
| Play-off | |
| Relégation | |
| Relégation |
