 |
 |
|
| 09.04.2022 | 18:30 | KAS Eupen | - | KV Oostende | 0:2 (0:1) | |
| 20:45 | Royal Antwerp FC | - | Cercle Brugge | 1:1 (0:0) | ||
| 10.04.2022 | 18:30 | Club Brugge KV | - | KV Mechelen | 2:0 (1:0) | |
| 18:30 | KAA Gent | - | Oud-Heverlee Leuven | 5:0 (1:0) | ||
| 18:30 | KV Kortrijk | - | RSC Anderlecht | 2:3 (1:1) | ||
| 18:30 | Union Saint-Gilloise | - | K Beerschot VA | 5:0 | ||
| 18:30 | Sporting Charleroi | - | SV Zulte Waregem | 3:0 (3:0) | ||
| 18:30 | RFC Seraing | - | KRC Genk | 0:2 (0:1) | ||
| 18:30 | Sint-Truidense VV | - | Standard Liège | 3:0 (2:0) |
| » Classement | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Union Saint-Gilloise | 34 | 24 | 5 | 5 | 78:27 | 51 | 77 |
| 2 |
|
Club Brugge KV | 34 | 21 | 9 | 4 | 72:37 | 35 | 72 |
| 3 |
|
RSC Anderlecht | 34 | 18 | 10 | 6 | 72:36 | 36 | 64 |
| 4 |
|
Royal Antwerp FC | 34 | 19 | 6 | 9 | 55:38 | 17 | 63 |
| 5 |
|
KAA Gent | 34 | 18 | 8 | 8 | 56:30 | 26 | 62 |
| 6 |
|
Sporting Charleroi | 34 | 15 | 9 | 10 | 55:46 | 9 | 54 |
| 7 |
|
KV Mechelen | 34 | 15 | 7 | 12 | 57:61 | -4 | 52 |
| 8 |
|
KRC Genk | 34 | 15 | 6 | 13 | 66:47 | 19 | 51 |
| 9 |
|
Sint-Truidense VV | 34 | 15 | 6 | 13 | 42:40 | 2 | 51 |
| 10 |
|
Cercle Brugge | 34 | 12 | 9 | 13 | 49:46 | 3 | 45 |
| 11 |
|
Oud-Heverlee Leuven | 34 | 10 | 11 | 13 | 47:58 | -11 | 41 |
| 12 |
|
KV Kortrijk | 34 | 9 | 10 | 15 | 43:48 | -5 | 37 |
| 13 |
|
KV Oostende | 34 | 10 | 7 | 17 | 34:61 | -27 | 37 |
| 14 |
|
Standard Liège | 34 | 9 | 9 | 16 | 32:51 | -19 | 36 |
| 15 |
|
KAS Eupen | 34 | 8 | 8 | 18 | 37:61 | -24 | 32 |
| 16 |
|
SV Zulte Waregem | 34 | 8 | 8 | 18 | 42:69 | -27 | 32 |
| 17 |
|
RFC Seraing | 34 | 8 | 4 | 22 | 30:68 | -38 | 28 |
| 18 |
|
K Beerschot VA | 34 | 4 | 4 | 26 | 33:76 | -43 | 16 |
| Play-off | |
| Play-off | |
| Relégation | |
| Relégation |
