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| 15.10.2021 | 18:30 | SV Seligenporten | - | Vatan Spor Aschaffenburg | 0:0 (0:0) | |
| 19:00 | 1. SC Feucht | - | Eintracht Bamberg | 0:0 (0:0) | ||
| 16.10.2021 | 14:00 | Würzburger FV | - | DJK Gebenbach | 1:1 (1:0) | |
| 15:00 | SpVgg Bayern Hof | - | DJK Vilzing | 0:1 (0:0) | ||
| 16:00 | 1. FC Sand | - | TSV Karlburg | 1:1 (0:1) | ||
| 16:00 | ASV Cham | - | SpVgg Ansbach | 2:2 (1:1) | ||
| 16:00 | TSV Abtswind | - | ATSV Erlangen | 1:2 (1:0) | ||
| 16:00 | TSV Großbardorf | - | DJK Ammerthal | 1:0 (0:0) | ||
| 17.10.2021 | 15:00 | DJK Bamberg | - | ASV Neumarkt | 3:2 (2:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SpVgg Ansbach | 16 | 12 | 2 | 2 | 36:11 | 25 | 38 |
| 2 |
|
DJK Vilzing | 16 | 12 | 1 | 3 | 35:14 | 21 | 37 |
| 3 |
|
Eintracht Bamberg | 16 | 11 | 3 | 2 | 42:11 | 31 | 36 |
| 4 |
|
ATSV Erlangen | 16 | 11 | 2 | 3 | 34:17 | 17 | 35 |
| 5 |
|
DJK Ammerthal | 16 | 9 | 2 | 5 | 38:25 | 13 | 29 |
| 6 |
|
ASV Neumarkt | 16 | 9 | 2 | 5 | 34:23 | 11 | 29 |
| 7 |
|
1. SC Feucht | 16 | 8 | 4 | 4 | 25:17 | 8 | 28 |
| 8 |
|
TSV Abtswind | 16 | 7 | 2 | 7 | 22:21 | 1 | 23 |
| 9 |
|
DJK Bamberg | 16 | 7 | 2 | 7 | 26:27 | -1 | 23 |
| 10 |
|
DJK Gebenbach | 16 | 6 | 2 | 8 | 34:35 | -1 | 20 |
| 11 |
|
TSV Großbardorf | 16 | 6 | 1 | 9 | 21:33 | -12 | 19 |
| 12 |
|
SpVgg Bayern Hof | 16 | 5 | 3 | 8 | 32:39 | -7 | 18 |
| 13 |
|
TSV Karlburg | 16 | 3 | 8 | 5 | 13:22 | -9 | 17 |
| 14 |
|
1. FC Sand | 16 | 3 | 5 | 8 | 14:29 | -15 | 14 |
| 15 |
|
SV Seligenporten | 16 | 3 | 2 | 11 | 21:41 | -20 | 11 |
| 16 |
|
Würzburger FV | 16 | 3 | 2 | 11 | 15:36 | -21 | 11 |
| 17 |
|
Vatan Spor Aschaffenburg | 16 | 2 | 4 | 10 | 14:34 | -20 | 10 |
| 18 |
|
ASV Cham | 16 | 2 | 3 | 11 | 19:40 | -21 | 9 |
| Promotion | |
| Play-off | |
| Relégation | |
| Relégation |
