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| 30.07.2022 | 20:00 | Crucero del Norte | - | Sarmiento de Resistencia | 0:3 (0:1) | |
| 23:00 | Atlético Paraná | - | Defensores Belgrano (VR) | 0:1 (0:0) | ||
| 31.07.2022 | 16:00 | Juventud Unida de Gualeguaychú | - | Gimnasia y Esgrima (CdU) | 0:3 (0:2) | |
| 20:00 | Sportivo Las Parejas | - | Douglas Haig | 1:0 (1:0) | ||
| 20:30 | Unión de Sunchales | - | San Martín de Formosa | 0:3 (0:0) | ||
| 21:00 | Boca Unidos | - | Racing de Córdoba | 1:1 (1:0) | ||
| 21:05 | Gimnasia y Tiro de Salta | - | Central Norte | 2:1 (1:0) | ||
| 01.08.2022 | 00:00 | Juventud Antoniana | - | Belgrano de San Francisco | 3:1 (1:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Racing de Córdoba | 21 | 12 | 8 | 1 | 36:11 | 25 | 44 |
| 2 |
|
Sarmiento de Resistencia | 21 | 11 | 8 | 2 | 29:10 | 19 | 41 |
| 3 |
|
Central Norte | 20 | 10 | 8 | 2 | 30:16 | 14 | 38 |
| 4 |
|
San Martín de Formosa | 20 | 10 | 5 | 5 | 34:21 | 13 | 35 |
| 5 |
|
Gimnasia y Esgrima (CdU) | 21 | 10 | 5 | 6 | 25:19 | 6 | 35 |
| 6 |
|
Gimnasia y Tiro de Salta | 21 | 10 | 4 | 7 | 21:21 | 0 | 34 |
| 7 |
|
Sportivo Las Parejas | 21 | 9 | 6 | 6 | 24:19 | 5 | 33 |
| 8 |
|
Douglas Haig | 21 | 9 | 5 | 7 | 31:20 | 11 | 32 |
| 9 |
|
Belgrano de San Francisco | 21 | 8 | 4 | 9 | 27:25 | 2 | 28 |
| 10 |
|
Crucero del Norte | 21 | 7 | 6 | 8 | 17:26 | -9 | 27 |
| 11 |
|
Juventud Antoniana | 21 | 7 | 5 | 9 | 18:25 | -7 | 26 |
| 12 |
|
Boca Unidos | 20 | 4 | 9 | 7 | 16:20 | -4 | 21 |
| 13 |
|
Defensores Belgrano (VR) | 21 | 6 | 3 | 12 | 18:25 | -7 | 21 |
| 14 |
|
Unión de Sunchales | 21 | 5 | 3 | 13 | 21:36 | -15 | 18 |
| 15 |
|
Atlético Paraná | 21 | 3 | 7 | 11 | 17:32 | -15 | 16 |
| 16 |
|
Defensores de Pronunciamiento | 20 | 3 | 7 | 10 | 12:29 | -17 | 16 |
| 17 |
|
Juventud Unida de Gualeguaychú | 20 | 4 | 3 | 13 | 16:37 | -21 | 15 |
| Play-off |
