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| 03.04.2022 | 21:00 | Defensores de Pronunciamiento | - | Defensores Belgrano (VR) | 1:1 (0:0) | |
| 21:00 | Gimnasia y Tiro de Salta | - | Sarmiento de Resistencia | 0:1 (0:1) | ||
| 21:15 | San Martín de Formosa | - | Central Norte | 0:0 (0:0) | ||
| 21:30 | Juventud Antoniana | - | Juventud Unida de Gualeguaychú | 1:0 (0:0) | ||
| 22:00 | Crucero del Norte | - | Gimnasia y Esgrima (CdU) | 2:0 (1:0) | ||
| 22:00 | Unión de Sunchales | - | Douglas Haig | 1:2 (0:1) | ||
| 23:00 | Sportivo Las Parejas | - | Racing de Córdoba | 0:0 (0:0) | ||
| 04.04.2022 | 00:00 | Atlético Paraná | - | Belgrano de San Francisco | 0:1 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Douglas Haig | 2 | 2 | 0 | 0 | 4:1 | 3 | 6 |
| 2 |
|
Sarmiento de Resistencia | 2 | 2 | 0 | 0 | 3:0 | 3 | 6 |
| 3 |
|
Crucero del Norte | 2 | 2 | 0 | 0 | 3:0 | 3 | 6 |
| 4 |
|
Racing de Córdoba | 2 | 1 | 1 | 0 | 2:0 | 2 | 4 |
| 5 |
|
San Martín de Formosa | 2 | 1 | 1 | 0 | 2:1 | 1 | 4 |
| 6 |
|
Juventud Antoniana | 2 | 1 | 1 | 0 | 1:0 | 1 | 4 |
| 7 |
|
Belgrano de San Francisco | 2 | 1 | 0 | 1 | 1:1 | 0 | 3 |
|
Gimnasia y Tiro de Salta | 2 | 1 | 0 | 1 | 1:1 | 0 | 3 | |
| 9 |
|
Gimnasia y Esgrima (CdU) | 2 | 1 | 0 | 1 | 2:3 | -1 | 3 |
| 10 |
|
Boca Unidos | 1 | 0 | 1 | 0 | 0:0 | 0 | 1 |
|
Central Norte | 1 | 0 | 1 | 0 | 0:0 | 0 | 1 | |
| 12 |
|
Defensores Belgrano (VR) | 2 | 0 | 1 | 1 | 2:3 | -1 | 1 |
| 13 |
|
Sportivo Las Parejas | 2 | 0 | 1 | 1 | 1:2 | -1 | 1 |
| 14 |
|
Defensores de Pronunciamiento | 2 | 0 | 1 | 1 | 1:3 | -2 | 1 |
| 15 |
|
Juventud Unida de Gualeguaychú | 2 | 0 | 0 | 2 | 0:2 | -2 | 0 |
| 16 |
|
Unión de Sunchales | 2 | 0 | 0 | 2 | 1:4 | -3 | 0 |
| 17 |
|
Atlético Paraná | 2 | 0 | 0 | 2 | 0:3 | -3 | 0 |
| Play-off |
