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| 31.07.2021 | 20:00 | Douglas Haig | - | Chaco For Ever | 0:1 (0:1) | |
| 20:30 | Boca Unidos | - | Crucero del Norte | 2:2 (0:0) | ||
| 01.08.2021 | 20:00 | Juventud Unida de Gualeguaychú | - | Unión de Sunchales | 0:0 (0:0) | |
| 20:00 | Gimnasia y Esgrima (CdU) | - | Racing de Córdoba | 1:3 (1:3) | ||
| 20:30 | Sarmiento de Resistencia | - | Defensores de Pronunciamiento | 2:2 (2:2) | ||
| 20:30 | Gimnasia y Tiro de Salta | - | Defensores Belgrano (VR) | 2:1 (2:1) | ||
| 21:00 | Sportivo Las Parejas | - | Central Norte | 2:1 (2:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Racing de Córdoba | 14 | 10 | 3 | 1 | 23:4 | 19 | 33 |
| 2 |
|
Gimnasia y Tiro de Salta | 14 | 8 | 5 | 1 | 19:10 | 9 | 29 |
| 3 |
|
Chaco For Ever | 14 | 6 | 6 | 2 | 21:12 | 9 | 24 |
| 4 |
|
Sportivo Las Parejas | 14 | 5 | 5 | 4 | 17:16 | 1 | 20 |
| 5 |
|
Defensores Belgrano (VR) | 14 | 6 | 2 | 6 | 18:19 | -1 | 20 |
| 6 |
|
Central Norte | 14 | 3 | 10 | 1 | 17:13 | 4 | 19 |
| 7 |
|
Boca Unidos | 14 | 3 | 8 | 3 | 18:18 | 0 | 17 |
| 8 |
|
Sarmiento de Resistencia | 14 | 4 | 5 | 5 | 15:18 | -3 | 17 |
| 9 |
|
Defensores de Pronunciamiento | 14 | 3 | 7 | 4 | 13:14 | -1 | 16 |
| 10 |
|
Juventud Unida de Gualeguaychú | 14 | 3 | 6 | 5 | 14:18 | -4 | 15 |
| 11 |
|
Belgrano de San Francisco | 14 | 2 | 8 | 4 | 16:19 | -3 | 14 |
| 12 |
|
Gimnasia y Esgrima (CdU) | 14 | 4 | 2 | 8 | 10:19 | -9 | 14 |
| 13 |
|
Unión de Sunchales | 14 | 2 | 7 | 5 | 12:16 | -4 | 13 |
| 14 |
|
Douglas Haig | 14 | 3 | 3 | 8 | 7:11 | -4 | 12 |
| 15 |
|
Crucero del Norte | 14 | 3 | 3 | 8 | 10:23 | -13 | 12 |
| Play-off | |
| Prochaine phase |
