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| 17.03.2023 | 18:30 | Arminia Bielefeld | - | 1. FC Nürnberg | 2:2 (2:0) | |
| 18:30 | 1. FC Heidenheim 1846 | - | Karlsruher SC | 5:2 (2:2) | ||
| 18.03.2023 | 13:00 | Jahn Regensburg | - | SC Paderborn 07 | 1:0 (0:0) | |
| 13:00 | Hamburger SV | - | Holstein Kiel | 0:0 (0:0) | ||
| 13:00 | SpVgg Greuther Fürth | - | 1. FC Magdeburg | 3:0 (0:0) | ||
| 20:30 | SV Darmstadt 98 | - | 1. FC Kaiserslautern | 2:0 (2:0) | ||
| 19.03.2023 | 13:30 | SV Sandhausen | - | FC St. Pauli | 0:5 (0:4) | |
| 13:30 | Hansa Rostock | - | Fortuna Düsseldorf | 2:5 (0:3) | ||
| 13:30 | Eintracht Braunschweig | - | Hannover 96 | 1:0 (0:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SV Darmstadt 98 | 25 | 15 | 7 | 3 | 40:21 | 19 | 52 |
| 2 |
|
1. FC Heidenheim 1846 | 25 | 14 | 8 | 3 | 51:28 | 23 | 50 |
| 3 |
|
Hamburger SV | 25 | 15 | 4 | 6 | 46:30 | 16 | 49 |
| 4 |
|
Fortuna Düsseldorf | 25 | 13 | 3 | 9 | 43:32 | 11 | 42 |
| 5 |
|
FC St. Pauli | 25 | 11 | 8 | 6 | 39:28 | 11 | 41 |
| 6 |
|
SC Paderborn 07 | 25 | 12 | 4 | 9 | 47:30 | 17 | 40 |
| 7 |
|
1. FC Kaiserslautern (N) | 25 | 10 | 9 | 6 | 39:34 | 5 | 39 |
| 8 |
|
Holstein Kiel | 25 | 8 | 10 | 7 | 41:40 | 1 | 34 |
|
Karlsruher SC | 25 | 10 | 4 | 11 | 41:40 | 1 | 34 | |
| 10 |
|
Hannover 96 | 25 | 8 | 7 | 10 | 33:33 | 0 | 31 |
| 11 |
|
SpVgg Greuther Fürth (A) | 25 | 7 | 9 | 9 | 33:37 | -4 | 30 |
| 12 |
|
1. FC Nürnberg | 25 | 8 | 5 | 12 | 22:37 | -15 | 29 |
| 13 |
|
1. FC Magdeburg (N) | 25 | 8 | 4 | 13 | 31:45 | -14 | 28 |
| 14 |
|
Jahn Regensburg | 25 | 7 | 5 | 13 | 25:40 | -15 | 26 |
| 15 |
|
Arminia Bielefeld (A) | 25 | 7 | 4 | 14 | 36:41 | -5 | 25 |
| 16 |
|
Eintracht Braunschweig (N) | 25 | 6 | 7 | 12 | 30:43 | -13 | 25 |
| 17 |
|
Hansa Rostock | 25 | 7 | 4 | 14 | 21:37 | -16 | 25 |
| 18 |
|
SV Sandhausen | 25 | 5 | 6 | 14 | 26:48 | -22 | 21 |
| Promotion | |
| Relégation | |
| Relégation | |
| Relégation |
